AbstractPurposeDetermine whether supraspinal mechanisms contribute to the sex difference in fatigability during and recovery from a dynamic and isometric fatiguing task with the knee extensors.MethodsTranscranial magnetic stimulation (TMS) and electrical stimulation were used to determine voluntary activation and contractile properties of the knee extensors in 14 men and 17 women (20.8±1.9 years) after a: 1) 60-s sustained, maximal voluntary isometric contraction (MVIC), and 2) dynamic fatiguing task involving 120 maximal voluntary concentric contractions with a 20% MVIC load.ResultsThere were no differences between men and women in the reduction of maximal torque during the sustained MVIC (54.4±18.9% vs 55.9±11.2%, P=0.49), nor in the decrease in power during the dynamic fatiguing task (14.7±20.1% vs. 14.2±18.5%, P=0.92). However, MVIC torque recovered more quickly for women than men after the sustained MVIC and the dynamic task (P
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