Contact heat evoked potentials: reliable acquisition from lower extremities

Publication date: Available online 7 January 2018
Source:Clinical Neurophysiology
Author(s): J Rosner, M Hubli, P Hostettler, PS Scheuren, J Rinert, JLK Kramer, M Hupp, A Curt, CR Jutzeler
ObjectiveTo investigate test-retest reliability of contact heat evoked potentials (CHEPs) from lower extremities using two different stimulation protocols, i.e., normal and increased baseline temperature.MethodsA total of 32 able-bodied subjects were included and a subset (N=22) was retested. CHEPs were recorded from three different dermatomes of the lower extremity (i.e., L2, L5, and S2). Test-retest reliability of CHEPs acquisition after simulation in various lower limb dermatomes using different stimulation protocolswas analyzed.ResultsThe study revealed an improved acquisition of CHEPS employing the increased baseline protocol, particularly when stimulating more distal sites, i.e., dermatome L5 and S2. Based on repeatability coefficients, CHEP latency (N2 potential) emerged as the most robust CHEP parameter. Although CHEP amplitudes (N2P2 complex) and pain ratings were decreased in the retest, amplitudes still showed fair to excellent intraclass correlation coefficients (ICCs) using normal baseline or increased baseline temperature, respectively.ConclusionsThis is the first study to demonstrate that CHEPs acquisition from the lower extremities is improved by increasing the baseline temperature of the thermode.SignificanceThis study highlights the usability of CHEPs as a viable diagnostic method to study small fiber integrity.



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