PURPOSE: To date, there have been mixed findings on whether greater anticipatory reductions in self-paced exercise intensity in the heat are mediated by early differences in rate of body heat storage. The disparity may be due to an inability to accurately measure minute-to-minute changes in whole-body heat loss. Thus, we evaluated whether early differences in rate of heat storage can mediate exercise intensity during self-paced cycling at a fixed rate of perceived exertion (RPE of 16; hard-to-very-hard work effort) in COOL (15[degrees]C), NORMAL (25[degrees]C) and HOT (35[degrees]C) ambient conditions. METHODS: On separate days, nine endurance-trained cyclists exercised in COOL, NORMAL and HOT conditions at a fixed RPE until work rate (measured after first 5-min of exercise) decreased to 70% of starting values. Whole-body heat loss and metabolic heat production were measured by direct and indirect calorimetry respectively. RESULTS: Total exercise time was shorter in HOT (57+/-20 min) relative to both NORMAL (72+/-23 min, P=0.004) and COOL (70+/-26 min, P=0.045). Starting work rate was lower in HOT (153+/-31 W) compared to NORMAL (166+/-27 W, P=0.024) and COOL (170+/-33 W, P=0.037). Rate of heat storage was similar between conditions during the first 4 min of exercise (all P>0.05). Thereafter, rate of heat storage was lower in HOT relative to NORMAL and COOL until 30-min of exercise (last common time-point between conditions; all P
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