Rising Incidence of Paediatric Inflammatory Bowel Disease in Canterbury, New Zealand, 1996-2015.

Background: The incidence of paediatric inflammatory bowel disease (IBD) around the world is increasing. Canterbury, New Zealand, has one of the highest Crohn's disease (CD) incidence rates published. This study aimed to document the incidence of paediatric IBD in Canterbury between 1996 and 2015. Methods: All patients diagnosed with IBD in Canterbury, while under 16 years of age, between 1 January 1996 and 31 December 2015 were identified. Demographic and disease phenotypic details were collected and entered into a secure database. Age-specific population data for Canterbury were obtained and annual incidence rates were then calculated. Results: The mean annual incidence rate over the 20-year period was 7.18/100 000 [95% CI 5.55-8.81] children. There was a four-fold increase in the incidence of paediatric IBD in Canterbury between 1996 and 2015. The ratio of CD to UC diagnosed was 8.4:1. Disease phenotype of CD and UC, based on the Paris classification, were comparable with other studies. Conclusion: The incidence of paediatric IBD in Canterbury has increased dramatically over the last two decades. Some of the observed incidence rates are among the highest documented anywhere in the world. The preponderance of CD over UC in the current study is the highest published. (C) 2017 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,

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