Clinical and demographic predictors of response to rTMS treatment in unipolar and bipolar depressive disorders

Depression is estimated to be the second most disabling condition by 2020 (Murray et al., 1997). More than 300 million people of all ages suffer from depression making it the leading cause of disability worldwide (World Health Organization, 2017). Unipolar depressive disorder (UDD) is associated with a variety of personal, cognitive, emotional, social and even economic impairments (Davidson et al., 2002; Marazziti et al., 2010; Shiozawa et al., 2015). Bipolar depressive disorder (BDD) is a recurrent, chronic and severe disease with significant impact on quality of life and considerable distress for social contacts and the society in general (Shiozawa et al., 2015).

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