Nature Reviews Genetics 18, 455 (2017). doi:10.1038/nrg.2017.53
Author: Darren J. Burgess
The observations of abnormal epigenomes in cancer has motivated the pursuit of epigenome-targeted drugs for cancer therapy, but despite the clinical approval of various drugs, their cellular mechanisms of action are only partially understood. A new study demonstrates that DNA methyltransferase inhibitors (DNMTi) and histone
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