Editor—I thank Drs Bolsin and Conroy1 for raising their concerns regarding a recent publication by Hajibandeh and colleagues2 in the British Journal of Anaesthesia. There is no doubt that the role of perioperative beta-blockade has come under close scrutiny since the 1990s,34 but it is misleading to describe the conclusions of the trial by Mangano and colleagues5 as 'baseless' despite there being some legitimate criticisms of its design and interpretation. The Mangano data have been used by others in other systematic reviews.67 We agree that data derived from the DECREASE trials are unreliable.
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