Incidence, clinicopathologic features, and fusion transcript landscape of translocation renal cell carcinomas

Abstract

Sir: We thank Wang et al for their interest and pertinent comments about our article “Incidence, clinicopathologic features, and fusion transcript landscape of translocation renal cell carcinomas”. We totally agree that the TFE3 break-apart FISH assay is sometimes difficult to interpret and may give rise to false-negatives. The authors question the FISH features observed in the newly described GRIPAP1-TFE3 fusion transcript.

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