Difference Between Respiratory Epithelial Adenomatoid Hamartomas and Small Malignant Tumors of the Olfactory Cleft on CT Scans in Forty-six Patients

Misdiagnosis of respiratory epithelial adenomatoid hamartomas for malignant tumors can lead to an aggressive surgical procedure, which is not necessary in the case of a respiratory epithelial adenomatoid hamartoma.

Detailed analysis of sinonasal CT scans without contrast can help to distinguish respiratory epithelial adenomatoid hamartomas of the olfactory cleft from small malignant tumors (T1 and T2) of the olfactory clefts.

Criteria in favor of diagnosis of small malignant tumors of the olfactory clefts on CT scans without contrast were unilaterality of masses in the olfactory clefts, large olfactory clefts /small olfactory clefts ratio ≥ 2 (sensibility at 91% and specificity at 100%), and presence of bone erosion.

Imaging criteria for the diagnosis of respiratory epithelial adenomatoid hamartomas of the olfactory cleft were the bilaterality of masses in the olfactory cleft, large olfactory cleft /small olfactory cleft ratio < 2, and no bone erosion.

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