Predominant slow EEG activity in healthy neonates: Transient thalamo-cortical dysrhythmia?

In healthy preterm- and term-born infants, EEG recorded during the days and weeks following birth comprises a relatively high degree of slow, delta activity (<4 Hz; e.g. Bell et al., 1991; Victor et al., 2005). This is substantially different from adult EEG, wherein alpha (8-12 Hz) is the dominant activity in healthy controls and predominant delta activity is characteristic of cerebral pathophysiology (e.g. Finnigan et al., 2016). The neurodevelopmental underpinnings and significance of this high degree of delta activity in healthy neonates, remains unclear and is the focus of this correspondence.

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