Haemodialysis alters peripheral nerve morphology in end-stage kidney disease

Neuropathy is the most common neurological complication of end-stage kidney disease (ESKD) occurring in 60 – 90% of patients (Krishnan and Kiernan, 2009; Hojs-Fabjan and Hojs, 2006; Laaksonen et al., 2002; Van den Neucker et al., 1998). The most prominent clinical features are paraesthesia, numbness, reduction in deep tendon reflexes, impaired vibration sense, muscle atrophy and weakness, which are indicative of damage to large myelinated nerve fibres. Typically, symptoms progress in a length-dependent fashion, with greater lower-limb than upper-limb involvement (Tilki et al., 2009; Krishnan et al., 2009; Krishnan and Kiernan, 2007).

from Physiology via xlomafota13 on Inoreader http://ift.tt/2dFrpHz
via IFTTT