Study of biochemical parameters in metabolic bone disease with chronic renal failure

2016-08-26T08-01-06Z
Source: International Journal of Research in Medical Sciences
Chitra A. Sathe, Vinaya P. Khamkar.
Background: Renal osteodystrophy and metabolic bone disease are terms that encompass a number of skeletal abnormalities, including osteomalasia, osteitis fibrosa cystica and impaired bone growth in children. The proposed work aimed to evaluate the status of bone health by estimating levels of elements like calcium, phosphorus, magnesium, alkaline phosphatase and alkaline phosphatase isoenzymes in serum of patients suffering from metabolic bone disease with chronic renal failure. Methods: The routine biochemical investigations were estimated by known standard methods and alkaline phosphatase isoenzymes were done by polyacrylamide slab gel electrophoresis. The assay values were statistically validated. Results: Serum calcium levels were significantly decreased (p


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