EP 71. The effect of intermittent theta burst stimulation over the dorsolateral prefrontal cortex on cortico-striatal connectivity

Fronto-striatal loops play an important role in various cognitive and emotional processes. Intermittent theta burst transcranial magnetic stimulation has been shown to increase regional excitability as well as functional connectivity of connected areas (Huang et al., 2005). The issue of choosing an optimal TMS intensity, which is interlinked with ethical and practical issues such as pain and muscle twitches, has not been explored in detail yet. Furthermore, the role of purely anatomical white matter tracts on functional connectivity has often not been taken into account when studying TMS effects.

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