GRINSPAN’S SYNDROME – a case report

2016-06-22T22-25-00Z
Source: Case Study and Case Report
Sadije Halimi, Mybera Ferizi, Antigona Gerqari, Nita Krasniqi, Mergita Ferizi.
Some internal disease can have impact in the skin. Grinspan syndrome is a syndrome characterized by presence of the triad: hypertension, diabetes mellitus and oral lichen planus . Grinspan in 1963 raported 23 patient having oral erosive lichen planus, associated with diabetes mellitus . In 1965 this triad was subsequently referred to as Grinspan syndrome by Grupper and Avul. Oral lichen planus is thought to be a result of the drugs used for treatment of hypertension and diabetes mellitus because drug therapy for diabetes mellitus and hypertension is capable of producing lichenoid reactions of the oral mucosa but this is not confirmed. This paper presents a case of mucocutaneous lichen planus associated with diabetes mellitus, and vascular hypertension. Our case is a 63 years old female. During intraoral examination, we can see white and ulcerated lesions all over the oral mucosa and pain during mastication, upon for the past one year ,associated with diabetes mellitus and arterial hypertension. Some internal disease can have impact in the skin. Grinspan syndrome is characterized by presence of the triad : hypertension, diabetes mellitus and oral lichen planus. The patients with oral lichen planus, should have a healthy lifestyle, well-balanced diet and stress reduction because this disease can be controlled but not eliminated.


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