OXIDANT AND ANTIOXIDANT STATUS IN PNEUMONIC GOATS WITH SPECIAL REFERENCE TO BACTERIAL ETIOLOGY

2016-05-02T00-23-08Z
Source: International Journal of Livestock Research
Sabry Ahmed Mousa, Soliman Mohammed Soliman.
The current investigation was carried out to evaluate oxidative stress serum biomarkers , antioxidant concentrations and isolation the most common etiology of bacterial pneumonia. Thirty goats of different age and sex belonging to private farms in Giza governorate were used in this study .All goats were exposed to complete and comprehensive clinical examination. The animals were divided into two equal groups apparently healthy (15), diseased (15). Blood samples were collected from both groups to determine enzymatic activates of superoxidase dismutase (SOD), glutathione peroxidase (GPX) in erythrocyte haemolysate, catalase (CAT), vitamin C, vitamin E and Albumin, aspartate aminotransaminase (AST), alanine aminotransaminase (ALT), urea and creatinine, as well as nasal swabs were collected for isolation of possible bacteria. The levels of CAT, SOD and GPX were significant higher (p≤0.05), vitamins C, E were significant decrease (p≤0.05), Significant decrease (p≤0.05) in Albumin in pneumonic goats. Of 30 goats nasal swabs, 73.3% (22/30) yielded different bacterial isolates. Mannheimia (Pasteurella) haemolytica was the predominant isolates (81.8%; 18/22) and other isolates . It can concluded that pneumonia served to produce oxidative stress in the goat with increased activities of antioxidant enzymes to facing excessive production of free radicals. For healthier status in small ruminant antioxidant supplementation is very important as supportive treatment in diseased cases and preventive aid in healthy cases. Keywords: Oxidative stress, Antioxidant, Vit. C, Bacteria, Pneumonia, goat


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