Effect of laser acupuncture in mild benign hypertensive female patients

2016-11-29T16-49-37Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Mohamed K. Seyam, Ghada M. Shawky.
Background: Recent studies have found that acupuncture treatments lower blood pressure. Acupuncture is a traditional Chinese medical technique of inserting needles at particular points on the body to balance the opposing forces of yin and yang and the smooth flow of qi. Laser acupoint technique is considers as saving time because it is performed in less time than needles acupuncture. Purpose: The aim of this study was to study the effect of laser acupuncture on lowering the primary type of hypertension in old female adults. Materials and Methods: Thirty female mild hypertensive patients with ranged age 50-59 years were enrolled in the study. Systolic and diastolic blood pressure evaluated by Mercury sphygmomanometer. Baseline blood pressure measured for each subject prior to the initiation of the treatment and after enrolled in of treatment program. The anthropometric data including age, duration of hypertension, height, weight and body mass index (BMI) was collected for both experimental and six weeks control groups. Results: after treating hypertension patients by the laser acupuncture for 6 weeks (twice per week session), both the systolic blood pressure (SBP) and diastolic blood pressure (DBP) decreased significantly (P

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Effect of Recasting of Ni-Cr Base Metal Dental Casting Alloys on the Corrosion Rate, Compositional Changes and Ion Release in Artificial Saliva and Saline Solution

2016-11-29T16-49-37Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
K Jayaprakash, K Harish Kumar Shetty, A Nityananda Shetty, Bantarahalli Thopegowda Nandish, Sowmya Rao.
Background: Environmental concerns are increasing rapidly, and the industry and public are more concerned about natural resources and recycling. Today, it is equally important to take into account cost, ecological factors in production and recycling of materials used in various fields. Purpose: The aim of this study was to evaluate corrosion rate, compositional changes and ion release of recasted Ni-Cr dental casting alloy Materials and Methods: Commercially available Ni -Cr alloy (Bellabond) was used in the study. The recasting was done without any addition of new alloys and recasted up to six times. Corrosion rate was determined by Tafel extrapolation method in artificial saliva in pH 2.3, 6.7 and in 0.9% saline solution at pH 7.3. The compositional changes were studied by Inductively coupled Plasma Atomic emission Spectroscopy (ICP-AES) method. Ion release during storage in artificial saliva and saline solution for one week and four weeks was detected by using atomic absorption spectroscopy (AAS). Results: The corrosion rate was found slightly increased with recasting numbers up to six times. The quantities of ions released increased as the recasting number increases. These changes were not clinically significant. During recasting procedure, there was a change in their alloy compositions, which increases the corrosion rate in recasted alloys. Conclusion: The recasting technique can be accepted in dental practices. This study showed the possibilities of safe usage of recasted alloys up to certain generations in dentistry and in later stages if it is not suitable for dentistry it can be directed to other fields of industries, where the biocompatibility is not a major requirement. This lowers the environmental burden, health hazards and protects imbalance of natural resources.


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Appraise the Health-Related Quality of Life among Trauma Patients

2016-11-29T16-49-37Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Ravi Kant Jain, Neelesh Dhadse, Chirag Sethi, Ravindra Kumar, Susmit Kosta.
Background: Limb injures is revolve a life-changing event that can cause significant disruptions in many important areas of life. Objectives: The objective of our study was to appraise the Health Related Quality of Life (HRQOL) and psychosocial factors associated with pain and disability in patients following Upper limb (UL) and lower limb (LL) trauma patients Materials and methods: A sample of convenience 300 adult male and female patients who met the inclusion criteria was included. A short form (36) health status questionnaire was filled by a single author from each patient after one year of follow up. This part was utilized to assess the QOL among limbs traumas patients. Results: Intraclass correlation coefficients were greater than 0.7 in five of the eight domains of SF 36 except mental health, social function and general health. Chronbachs α was higher the 0.8 all the domains except in social function domain. There was no difference in Health Related Quality of Life in patients with upper and lower limb trauma. However there was significant difference in 4 domains related to physical components of SF 36 survey form between male and females. Conclusion: Both upper and lower limb trauma similarly affects the Health Related Quality of Life in all age group of patients.


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Determination of insertion depth of flexible laryngeal mask airway in pediatric population—A prospective observational study

The purpose of this study was to determine the ideal insertion depth of the flexible laryngeal mask airway (FLMA) by elucidating the relationships between insertion depth and patient's age, body weight, height, and other parameters. We also evaluated an insertion technique that uses the change in intracuff pressure for proper positioning of the FLMA in cases where it is difficult to sense resistance during FLMA insertion.

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Mutations in IL36RN are associated with geographic tongue

Abstract

Geographic tongue (GT) is a benign inflammatory disorder of unknown etiology. Epidemiology and histopathology in previous studies found that generalized pustular psoriasis (GPP) is a factor associated with GT, but the molecular mechanism remains obscure. To investigate the mechanism of GT, with and without GPP, three cohorts were recruited to conduct genotyping of IL36RN, which is the causative gene of GPP. In a family spanning three generations and diagnosed with only GT ("GT alone"), GT was caused by the c.115+6T>C/p.Arg10ArgfsX1 mutation in the IL36RN gene. An autosomal dominant inheritance pattern with incomplete penetrance was observed. In the cohort consisting of sporadic cases of "GT alone" (n = 48), significant associations between GT and three IL36RN variants (c.115+6T>C/p.Arg10ArgfsX1, c.169G>A/p.Val57Ile and c.29G>A/p.Arg10Gln) were shown. In the GPP patient cohort (n = 56) and GPP family member cohort (n = 67), a significant association between the c.115+6T>C mutation and the simultaneous presence of GPP and GT was observed when compared to the presence of GPP without GT (P < 0.05). Biopsies revealed similarities among GT patients with different genotypes (AA, Aa and aa), with the neutrophils prominently infiltrating the epidermis. Western-blot analysis showed that the expression ratio of IL-36Ra/IL-36γ in lesioned tongues with individuals harboring different genotypes (AA, Aa and aa, n = 3, respectively) decreased significantly compared to controls (n = 3). We describe the mechanism of GT for the first time: some cases of GT are caused by IL36RN mutations, while those lacking mutations are associated with an imbalance in expression between IL-36Ra and IL-36γ proteins in tongue tissue.

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Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression [Genetics]

Triple-negative breast cancer (TNBC) has the worst prognosis of any breast cancer subtype. To better understand the genetic forces driving TNBC, we performed a transposon mutagenesis screen in a phosphatase and tensin homolog (Pten) mutant mice and identified 12 candidate trunk drivers and a much larger number of progression genes....

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Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells [Genetics]

Rereplication generates double-strand breaks (DSBs) at sites of fork collisions and causes genomic damage, including repeat instability and chromosomal aberrations. However, the primary mechanism used to repair rereplication DSBs varies across different experimental systems. In Drosophila follicle cells, developmentally regulated rereplication is used to amplify six genomic regions, two of...

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