Παρασκευή 12 Αυγούστου 2016

Archbishop has severe allergic reaction to acetaminophen

By Associated Press

MILWAUKEE — Milwaukee's archbishop says his guardian angel was working overtime when he had a severe allergic reaction to acetaminophen that could have been deadly.

Archbishop Jerome Listecki tells WISN-TV that he took some cough medicine before heading to a meeting Monday and didn't realize it contained the Tylenol ingredient acetaminophen. His face and throat began to swell and soon he could only whisper and was having trouble breathing.

Listecki says he was able to walk to the parking lot and call 911. Paramedics gave him an epinephrine shot and a priest gave him the sacrament of the sick.

The archbishop says he received another shot of epinephrine in the ambulance and was kept overnight at Columbia St. Mary's Hospital.



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Driver Engineer/Paramedic or EMT - Citrus Sheriff Fire Rescue

CITRUS SHERIFF FIRE RESCUE 1 DR. MARTIN LUTHER KING JR. AVENUE INVERNESS, FLORIDA 34450 Updated: August 09, 2016 Classification: Driver Engineer/Paramedic or EMT The Citrus Sheriff Fire Rescue is currently building an ongoing eligibility list for Driver Engineer/Paramedic or EMT. The department anticipates hiring for 4 open positions in the upcoming future. Citrus County requires both FireTEAM and a ...

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Paramedic (Domestic Project Team) - Remote Medical International

Domestic Project Team (DPT) Culture: We are seeking candidates that are truly passionate about providing excellent clinical care in proactive, professional, and diplomatic manner. This role is more than a mere set of requirements; it is an opportunity for you share your professional aspirations in an environment which encourages innovative practices, flexibility, and professional growth. If you are ...

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Self-directed arm therapy at home after stroke with a sensor-based virtual reality training system

The effect of rehabilitative training after stroke is dose-dependent. Out-patient rehabilitation training is often limited by transport logistics, financial resources and a lack of motivation/compliance. We st...

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Evaluate all newly diagnosed mild-moderate renal dysfunction patients for primary hypothyroidism

2016-08-12T06-59-24Z
Source: International Journal of Research in Medical Sciences
Karethimmaiah Hareesha Babu, Vijaya Sarathi, Rakesh Boppana.
Background: Hypothyroidism often presents to nephrologists with elevated serum creatinine which may lead to unnecessary evaluation including renal biopsy. Methods: We retrospectively analysed the data of 24 patients who presented to the department of nephrology at our institute with anasarca/facial puffiness or elevated serum creatinine and diagnosed to have hypothyroidism with TSH >40 µIU/ml. Results: Twelve patients presented with generalised edema, eight patients for evaluation of deranged serum creatinine and four patients with both generalised edema and deranged serum creatinine. Age (r=0.696, p


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Drug prescribing pattern in ulcerative colitis in a tertiary care hospital: an observational study

2016-08-12T06-39-58Z
Source: International Journal of Basic & Clinical Pharmacology
Mukunda Narayanareddy, Eesha B. R., Tara V. Shanbhag, Smita Shenoy.
Background: Ulcerative colitis (UC) is an inflammatory disease of colon and rectum of uncertain etiology. The clinical course of UC is marked by exacerbations and remissions. Furthermore there is limited data available on the management of ulcerative colitis from India. Hence, the present study was undertaken to study the drug prescribing pattern in ulcerative colitis. Methods: A retrospective case record based observational study was done at Kasturba Hospital, Manipal, India from 1st January 2009 to 31st December 2010. Patients diagnosed to have UC during our study period based on clinical, endoscopic and histopathological evidence were included in the study. SPSS 17 software package was used for statistical calculations. Descriptive statistics was used to analyze the data. Results: The total number of patients diagnosed to have UC during our study period was 83.The peak incidence of disease was in the age group of 30-39 years and it was more common in males. The prescription rate of aminosalicylates, glucocorticoids and immunosuppressants were 96.3, 54.3, and 18.5% respectively. Mesalamine, prednisolone, and azathioprine were the commonly prescribed drugs in each class. The commonly prescribed treatment regimen was combination of aminosalicylates with glucocorticoids (43.2%). Conclusions: Ulcerative colitis was more common in males. Aminosalicylates were the commonly prescribed drugs and a combination of aminosalicylate and steroid was frequently used regimen in our study.


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Evaluation of the anti-inflammatory activity of dipyridamole in acute and chronic experimental models in albino rats

2016-08-12T06-39-58Z
Source: International Journal of Basic & Clinical Pharmacology
Vishwaprakash M. K., Laveesh M. R., Somashekara S.C.
Background: Cyclic nucleotides, particularly cyclic AMP, have an important regulatory role in a variety of inflammatory processes. The concentration of cAMP can be influenced by either inhibition of phosphodiesterase enzyme or by activating adenylate cyclase enzyme. The present study was undertaken to evaluate the anti-inflammatory activity of dipyridamole a selective (PDE6) phosphodiesterase inhibitor; on acute and chronic experimental models in albino rats. Methods: Anti-inflammatory activity was evaluated by using carrageenan-induced rat hind paw oedema model for assessing acute anti-inflammatory activity. The normal paw volume (0 hour) and the volume of injected paw (3 hour) were measured by using plethysmometer. Assessment of chronic anti-inflammatory activity was carried out using formalin-induced rat paw edema model. The paw volume was measured at 0 hour and on 7th day after injection of formalin by using plethysmometer. The results obtained were compared with the control and the standard anti-inflammatory drug, indomethacin. Results: The results indicated that dipyridamole has anti-inflammatory action in both acute and chronic inflammatory models. But statistically significant anti-inflammatory action was seen only with the chronic inflammatory model (0.11±0.05 units, p=0.02). Anti-inflammatory activity could be due to inhibition of inflammatory cells and mediators especially histamine, leukotrienes and eicosanoids. Conclusions: Selective phosphodiesterase inhibitors could be a source of valuable anti-inflammatory drugs, in addition to currently available steroidal and non-steroidal anti-inflammatory agents.


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