Because of the rising prevalence of cancer, many individuals are living with the side effects of cancer and its treatment. One of the possible side effects is chemotherapy-induced peripheral neuropathy (CIPN). The purpose of the study was to examine the effect of lower limb closed kinematic chain exercises on balance in patients with CIPN. The study design was a single group pre-post experimental one. The study was conducted at a tertiary care cancer hospital. A total of 25 individuals with CIPN and aged 30 years and older were recruited using the Modified Total Neuropathy Score higher than 5. Closed kinematic chain exercises were administered for a total of 15 sessions over 3 weeks. Patients were assessed at baseline using the mTNS and Berg Balance Scale and reassessed after 15 sessions. mTNS score decreased from 13.88 at baseline to 6.5 at the end of intervention, and the Berg Balance Scale increased from 26 at baseline to 42 after intervention, with a P-value of 0.00001. Exercises were effective in reducing symptoms in neuropathy and improving balance. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
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Τρίτη 4 Οκτωβρίου 2016
Predictors of physical independence at discharge after stroke rehabilitation in a Dutch population.
The aim of this study was to identify predictors, available at admission, of physical independence at discharge from inpatient rehabilitation. Secondary aims were to identify predictors of functional gain and length of stay (LOS). We included 1310 adult stroke patients who were admitted for inpatient rehabilitation in five Dutch rehabilitation centres. Data on the Utrecht Scale for Evaluation of Clinical Rehabilitation at admission and discharge (physical and cognitive independence, mood, pain and fatigue), age, sex and in a subsample stroke characteristics as well were collected. A prediction model was created using random coefficient analysis. None of the stroke characteristics were independently associated with physical independence or functional gain at discharge, or LOS. Higher physical and cognitive independence scores and severe pain at admission were predictors of higher physical independence scores at discharge. Furthermore, lower physical independence scores, higher cognitive independence scores, less pain at admission and younger age predicted more functional gain. Finally, lower physical and cognitive independence scores at admission and younger age predicted longer LOS. Physical independence at admission was the most robust predictor for rehabilitation outcome in a Dutch rehabilitation setting. To a lesser extent, age, cognitive independence and pain predicted rehabilitation outcome after stroke. Treatment of cognition and pain should be taken into account during rehabilitation. Further work needs to be carried out to establish whether focusing on these factors improves outcome after rehabilitation. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
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Reconstructing ERP amplitude effects after compensating for trial-to-trial latency jitter: A solution based on a novel application of residue iteration decomposition
Source:International Journal of Psychophysiology, Volume 109
Author(s): Guang Ouyang, Werner Sommer, Changsong Zhou
Stimulus-locked averaged event-related potentials (ERPs) are among the most frequently used signals in Cognitive Neuroscience. However, the late, cognitive or endogenous ERP components are often variable in latency from trial to trial in a component-specific way, compromising the stability assumption underlying the averaging scheme. Here we show that trial-to-trial latency variability of ERP components not only blurs the average ERP waveforms, but may also attenuate existing or artificially induce condition effects in amplitude. Hitherto this problem has not been well investigated. To tackle this problem, a method to measure and compensate component-specific trial-to-trial latency variability is required. Here we first systematically analyze the problem of single trial latency variability for condition effects based on simulation. Then, we introduce a solution by applying residue iteration decomposition (RIDE) to experimental data. RIDE separates different clusters of ERP components according to their time-locking to stimulus onsets, response times, or neither, based on an algorithm of iterative subtraction. We suggest to reconstruct ERPs by re-aligning the component clusters to their most probable single trial latencies. We demonstrate that RIDE-reconstructed ERPs may recover amplitude effects that are diminished or exaggerated in conventional averages by trial-to-trial latency jitter. Hence, RIDE-corrected ERPs may be a valuable tool in conditions where ERP effects may be compromised by latency variability.
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Ultrasound Guided Liver Biopsy with Gelatin Sponge Pledget Tract Embolization in Infants Weighing Less Than 10 kg.
Purpose: To describe and assess the technical success and safety of ultrasound guided liver biopsy with gelatin sponge pledget tract embolization technique in infants less than 10 kg across three tertiary pediatric hospitals. Materials and Methods: There were 67 pediatric patients weighing less than 10 kg (36 males; 31 females; average age 202 days; average weight 6 kg, range 1.5 kg to 9.9 kg) referred for liver biopsy performed with ultrasound guidance and gelatin sponge pledget tract embolization during a two year period. Patient history, procedural records, and clinical follow-up documents were retrospectively reviewed. Results: A total of 67 procedures were included. There was 100% technical success rate and all samples obtained provided adequate tissue for histological assessment. Average number of 18G biopsy passes was 3 (range 1-6). There were no procedure-related deaths. There was one complication (1%) in an 5 kg infant who was readmitted 36 hours after biopsy with a fever and after antibiotics were administered fully recovered. Biliary atresia was the most common underlying diagnosis (20%), while others included acute rejection (16%), biliary obstruction (7%). Conclusions: Ultrasound guided percutaneous liver biopsy with gelatin sponge pledget tract embolization technique in children less than 10 kg is safe, effective, and use of this technique may lead to a reduction in rates of adverse events reported in other pediatric series. (C) 2016 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,
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Δευτέρα 3 Οκτωβρίου 2016
New "ICU" pressure chamber at Oslo University Hospital:
This is about time.Did 50M."Club Dive"in the old one, 1985... This is a different world. TV/Video/Radio/Streaming.Full intensive care capable. Looking very good, IMO. On the roof of the Emergency building(50 tonn(+The Hwy.building),-near the Heliport.) And: The worlds deepest concert -303 Meters(994feet) below the surface of the sea: https://youtube/_YtCHHpZNxo (Time 59,30=This is the closest thing to crasy) Full documentary,(-or just the concert? It starts at 28,52) :http://ift.tt/1NuXCu7 ExEMTNor
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New "ICU" pressure chamber at Oslo University Hospital:
This is about time.Did 50M."Club Dive"in the old one, 1985... This is a different world. TV/Video/Radio/Streaming.Full intensive care capable. Looking very good, IMO. On the roof of the Emergency building(50 tonn(+The Hwy.building),-near the Heliport.) And: The worlds deepest concert -303 Meters(994feet) below the surface of the sea: https://youtube/_YtCHHpZNxo (Time 59,30=This is the closest thing to crasy) Full documentary,(-or just the concert? It starts at 28,52) :http://ift.tt/1NuXCu7 ExEMTNor
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New "ICU" pressure chamber at Oslo University Hospital:
This is about time.Did 50M."Club Dive"in the old one, 1985... This is a different world. TV/Video/Radio/Streaming.Full intensive care capable. Looking very good, IMO. On the roof of the Emergency building(50 tonn(+The Hwy.building),-near the Heliport.) And: The worlds deepest concert -303 Meters(994feet) below the surface of the sea: https://youtube/_YtCHHpZNxo (Time 59,30=This is the closest thing to crasy) Full documentary,(-or just the concert? It starts at 28,52) :http://ift.tt/1NuXCu7 ExEMTNor
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