A careful endoscopic surveillance of Barrett's oesophagus is warranted to prevent esophageal cancer.
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Σάββατο 16 Ιουλίου 2016
Barrett's oesophagus and associated dysplasia are not equally distributed within the esophageal circumference
Estimation of gastric pH in cynomolgus monkeys, rats, and dogs using [13C]-calcium carbonate breath test
The determination of gastric pH is important for the confirmation of efficacy of anti-secretory drugs. However, current methods for measurement of gastric pH provide significant stress to animals and humans.
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Are neuroticism and extraversion related to morning cortisol release in healthy older people?
Source:International Journal of Psychophysiology
Author(s): S. Puig-Perez, M. Almela, M.M. Pulopulos, V. Hidalgo, A. Salvador
The cortisol awakening response (CAR) is a discrete component of the hypothalamic-pituitary-adrenal axis (HPA-axis) function that has been widely related to both health and some personality traits. There is evidence that neuroticism and extraversion affect health and well-being and play a damaging or protective role, respectively. In this study, we aimed to explore the relationship between these personality dimensions and morning cortisol concentrations in people aged 55 or older. To do so, morning saliva samples were collected on two consecutive weekdays from a total of 160 older men and women. Neuroticism and extraversion were assessed using the Eysenck Personality Questionnaire-Revised, short form (EPQ-RS). Our results showed that neuroticism was negatively related to overall morning cortisol concentrations (AUCG) (i.e., area under the curve with respect to the ground in cortisol levels), but not to the CAR. When we explored sex as a moderator, neuroticism was related to a CAR of increased magnitude in women, although this relationship was not significant in men. No significant relationships were found between extraversion and CAR or AUCG, regardless of sex. In conclusion, neuroticism – but not extraversion – was related to HPA-axis function in older adults, highlighting its potential relevance in health alterations associated with HPA-axis functioning.
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Barrett's oesophagus and associated dysplasia are not equally distributed within the esophageal circumference
A careful endoscopic surveillance of Barrett's oesophagus is warranted to prevent esophageal cancer.
from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/29DeymS
via IFTTT
Estimation of gastric pH in cynomolgus monkeys, rats, and dogs using [13C]-calcium carbonate breath test
The determination of gastric pH is important for the confirmation of efficacy of anti-secretory drugs. However, current methods for measurement of gastric pH provide significant stress to animals and humans.
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Cross-education of wrist extensor strength is not influenced by non-dominant training in right-handers
Abstract
Purpose
Cross-education of strength has been proposed to be greater when completed by the dominant limb in right handed humans. We investigated whether the direction of cross-education of strength and corticospinal plasticity are different following right or left limb strength training in right-handed participants.
Methods
Changes in strength, muscle thickness and indices of corticospinal plasticity were analyzed in 23 adults who were exposed to 3-weeks of either right-hand strength training (RHT) or left-hand strength training (LHT).
Results
Maximum voluntary wrist extensor strength in both the trained and untrained limb increased, irrespective of which limb was trained, with TMS revealing reduced corticospinal inhibition.
Conclusions
Cross-education of strength was not limited by which limb was trained and reduced corticospinal inhibition was not just confined to the trained limb. Critically, from a behavioral perspective, the magnitude of cross-education was not limited by which limb was trained.
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A study of electrocardiographic changes in acute cerebrovascular accidents
2016-07-16T09-29-24Z
Source: International Journal of Medical Science and Public Health
Srikanth Tandur, Suraj Sundaragiri.
Background: Cardiac abnormalities occur in majority of patients after cerebrovascular accidents, accounting for unexpected deaths during the first month. The most common disturbances include electrocardiogram (ECG) abnormalities, cardiac arrhythmias, and myocardial injury and dysfunction. Objectives: The present study aims to determine the electrocardiographic changes observed in different types of stroke, their prevalence, and to establish the prognostic significance of the ECG changes. Material and Methods: This prospective study was carried out in a superspeciality hospital during 2 years which comprised of 100 patients. Patients were categorized based on computerized tomography findings into cerebral infarction, intracerebral hemorrhage, and subarachnoid hemorrhage. ECG changes are interpreted with rate, rhythm, and abnormalities and conclusions were derived. Results: Stroke was most common in 5th and 6th decade. Cerebral infarction formed the largest group. Males had higher preponderance. Hypertension was the most common risk factor. In total, 74% had electrocardiographic abnormality. ECG changes are more common among cerebral hemorrhage and subarachnoid hemorrhage. Most common ECG abnormality was prolonged QTc interval. Overall immediate mortality was 23%. It was high in cerebral hemorrhage. Morality was high in patients with abnormal ECG, mostly with prolonged QTc and with T-wave inversion. Conclusion: Patients with cerebrovascular accidents often have abnormal ECG in the absence of known organic heart disease or electrolyte imbalance. These ECG changes are more common in hemorrhagic than ischemic stroke. The mortality in these patients did not relate to the ECG changes seen but was dependent on the type of cerebrovascular accident and the level of consciousness on admission.
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