STUDY OF DRUG-DRUG INTERACTION IN MEDICINE DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL

2016-08-09T05-51-53Z
Source: Indo American Journal of Pharmaceutical Research
Safdar M*, Nataraj G.R, Nivil Joseph, Neethu George.
Many drugs are going to be prescribed in patients who admitted to medicine department. These drugs are capable of causing a number of adverse drug-drug interactions (DDI) some of which may be fatal. Polypharmacy is one of the leading cause of DDI in patients. Thus DDI associated with these drugs may lead to non-compliance and at times discontinuation of therapy. To evaluate drug-drug interactions in patients admitted in medicine department. It is a prospective-observational study. This study included hospital out-patients treated in Medicine department. Data was collected from the medical records of In-patients which includes patients demographic details, medication history, social history, treatment chart, status and drug-drug interaction is assessed by using micromedex and other tertiary resources and documented in a suitably designed data collection form. A total of 200 patients were enrolled in the study in that 36% are belonging to age group 31-50. More patients were males.41.5% moderate interactions and 11.5% mild interactions were found. Number of drugs prescribed and age is playing an important role in drug-drug interaction.


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