AN OVERVIEW ON TRANSDERMAL DRUG DELIVERY

2016-08-09T05-51-53Z
Source: Indo American Journal of Pharmaceutical Research
Abhinay Chhetri*, Dr.Biplab Kumar Dey.
Transdermal drug delivery system is also known as a transdermal patch or skin patch which deliver a specific dose of medication to the systemic circulation. It is a medicated adhesive patch. Morphological, biophysical and physicochemical properties of the skin are to be considered when therapeutic agents are delivered through the human skin for systemic effects. Transdermal drug delivery system can improve the therapeutic efficacy and safety of the drugs because drug delivered through the skin at a predetermined and controlled rate. Skin is the important site of drug application for both the local and systemic effects. Characterization of transdermal patch is use to check its quality, size, time of onset & duration, adhesive property, thickness, weight of patch, moisture of content, uniformity & cutaneous toxicological studies. This review article provides an overview of TDDS, its advantages over conventional dosage forms, drug delivery routes across human skin, permeation enhancers, and various components of transdermal patches, types of transdermal patches, methods of preparation and its methods of evaluation.


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