A RARE CASE REPORT ON DRUGs’ ADVERSE REACTION ON SODIUM VALPROATE: UNUSUAL COMPLAINTS OF VERTIGO, DIZZINESS AND INCREASED SALIVATION

2016-08-09T05-51-53Z
Source: Indo American Journal of Pharmaceutical Research
Elizabeth Phoeba Paul*, Jasmin Elizabeth Thomas, Josna James, Geethu C, T Sivakumar.
Sodium Valproate usage in the field of medicine has been started earlier in the 1960s. Toxicity has been rising steadily nowadays and its signs and symptoms of include CNS abnormalities, respiratory depression, nausea or vomiting and abnormalities in laboratory investigations include elevated serum Sodium Valproate levels, hypernatremia, elevated anion gap metabolic acidosis, hyperosmolality, hypocalcemia, and hyperammonemia. At this juncture, we report a case with seizures who was given Sodium Valproate and was switched on to Phenytoin due to toxicity as the patient complained of unusual adverse drug reactions.


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