EP 16. Nucleus accumbens stimulation in severe obsessive compulsive disorder

Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2–3% and often bears a high level of suffering and a great impact on psychosocial functioning and quality of life. International guidelines agree on cognitive behavioural therapy and pharmacological interventions as first line treatments. Only 70% of patients with OCD respond to these treatments, a substantial proportion of patients remain severely affected, for these patients deep brain stimulation of the nucleus accumbens (NAcc-DBS) might be a useful neuromodulative therapy approach.

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