High Resolution MEG Source Imaging Approach to Accurately Localize Broca’s Area in Patients with Brain Tumor or Epilepsy

Currently, magnetoencephalography (MEG) has been routinely used as a non-invasive pre-surgical functional mapping tool in patients with brain tumors and/or epilepsies. This is mainly due to MEG's better localization accuracy (in several millimeters for cortical areas) (Huang et al., 2006; Leahy et al., 1998; Niranjan et al., 2013) than scalp electroencephalography (EEG), and MEG's higher temporal resolution (in 1 millisecond) than several other commonly known functional mapping techniques, such as functional magnetic resonance imaging (fMRI, in seconds) and Positron emission topography (PET, in minutes).

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