FV 1. Perilesional activation in poststroke language recovery

Poststroke aphasia recovery evolves in time. Increased perilesional activity associated with treatment-related language improvements has been confirmed in the chronic phase (Fridriksson et al., 2011), but has not yet been systematically demonstrated during the early phases of stroke recovery. The pathophysiology of stroke suggests that perilesional reorganisation evolves within days, lasting for months after stroke, while increased neuronal excitability might provide a basis for perilesional neuroplasticity (Schiene et al., 1999).

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