EP 35. Influence of gender on personality-brain structure relationships

Previous studies have shown that males and females differ in personality. In particular, gender differences have been reported for neuroticism and agreeableness (Costa et al., 2001), with women scoring higher on these two traits than men. Although gender has also been shown to influence brain structure, effects of gender on personality – brain relationships have hardly been investigated. Indeed, most studies treated gender as a covariate of no interest. (Hu et al., 2011). In this study, we used whole brain voxel-based morphometry (Ashburner and Friston, 2000) to investigate the influence of gender on associations between personality traits (assessed by the NEO FFI) and grey matter volume (GMV) in a large sample of 182 males and 182 females.

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