THE ROLE OF DECOY CELLS IN URINE CYTOLOGY IN DETECTION OF POLYOMAVIRUS INFECTION IN POST RENAL TRANSPLANT PATIENTS

2016-07-18T01-07-28Z
Source: International Journal of Current Research and Review
Pavithra P., Praveen S. Kumar.
Objective: To assess the role of urine cytology as a simple and noninvasive tool in assessment of post renal transplant polyoma virus infection Case Report: Polyoma virus BK can infect the renal transplant patients on immunosuppressive therapy resulting in progressive renal allograft dysfunction and graft loss. We report a case of 42 year old male who underwent renal transplant six weeks ago followed by immunotherapy, had signs of rejection in the immediate post- transplant period for which he was put on antithymocyte globulin. He now presented with dysuria and urine cytology was done. Viral cytopathic effect in the form of enlarged nucleus with basophilic viral intranuclear inclusions and ground glass chromatin known as decoy cells were seen. Conclusion: Urine cytology can be used as a simple and cost effective screening method for monitoring the renal transplant patients for polyoma virus allograft nephropathy


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