Massive Serum Creatine Kinase Elevation Due To Olanzapine Treatment In An Adolescent With Bipolar Disorder

2016-03-03T18-49-13Z
Source: Çocuk ve Gençlik Ruh Sağlığı Dergisi / Turkish Journal of Child and Adolescent Mental Health
Tanıdır C, Eseroğlu T, Bozbey S, Adaletli H, Üneri ÖŞ.
There are case reports that indicate creatine kinase (CK) elevation due to atypical antipsychotic treatment in literature. In this article we aimed to disscuss the clinical course, differential diagnosis and the mechanism of CK elevation in an adolescent with bipolar disorder whose serum CK levels increased to 32440 U/L (normal range: 30-200 U/L) after short-term olanzapine treatment. The mechanism of CK elevation due to antipsychotic use is not clear; however currently, when compared to cases like this presented one, it seems adequate to stop the antipsychotic medication and monitor serum CK levels periodically if other possible medical causes are excluded.


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