Will the 8th editions of the UICC & AJCC staging manuals improve the pathological diagnosis of extranodal extension from cervical lymph nodes?

Garcia et al. [1] present noteworthy data having applied the criteria of the 8th edition of the Union for International Cancer Control (UICC) [2] to a series of mucosal squamous cell carcinomas of the head and neck which had originally been reported using the criteria of earlier editions. It is interesting they do not use the term “extranodal extension” (ENE), which has been introduced into the 8th editions of both the UICC and American Joint Committee on Cancer (AJCC) [3] staging manuals, except where the new criteria are quoted in Table 1, instead preferring “extracapsular spread” (ECS).

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