Access to (Hetero)arylated Selenophenes via Palladium-catalysed Stille, Negishi or Suzuki Couplings or C−H Bond Functionalization Reaction

Abstract

(Hetero)aryl-substituted selenophenes exhibit important physical properties especially for optoelectronics. Palladium-catalysed coupling reactions currently represent the most efficient methods to prepare such (hetero)arylated selenophene derivatives. Initially, Stille coupling was the most efficient reaction for the synthesis of these compounds; however, over the last decade, Suzuki coupling has become the most commonly employed. Recently, Pd-catalysed arylation via the C−H bond activation of selenophenes has proved to be a very convenient alternative method for the preparation of several arylated selenophenes as there is no need to prepare organometallic derivatives. In this Review, the progress and substrate scope in the synthesis of both C2- and C3-arylated selenophenes via Pd-catalysis are summarized.

Selenophenes stereotypes: The progress and substrate scope of the palladium catalyzed synthesis of both C2- and C3-arylated selenophenes are summarized in this Review—from Stille, Suzuki, and Negishi coupling through to C−H bond activation

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