A Case of Steroid-Responsive Encephalopathy Associated With Autoimmune Thyroiditis (Hashimoto's Encephalopathy)

2016-07-25T17-20-02Z
Source: Düşünen Adam: The Journal of Psychiatry and Neurological Sciences
Mustafa Tatlı.
Hashimoto's Encephalopathy (HE) is a syndrome which represents itself with diverse neuropsychiatric symptoms and high titers of anti-thyroid antibodies, the syndrome has no specific radiological or EEG findings and it can be dramatically resolved with corticosteroid treatment. HE can show different clinical findings such as, confusion, stupor, coma, stroke like episodes, epileptic seizures, myoclonus, behavioral changes, hallucinations and delusions. The cause of HE has been proposed to be autoimmune because of it's association with other immunologic disorders, female predominance, inflammatory findings in cerebrospinal fluid and response to treatment with streoids. Because the disease has a wide range of symptom scala and has no specific radiological findings and also has no proven pathogenetic mechanism that can explain the occurence of the disease it is thought that the diagnosis of the syndrome can be delayed or the disease can be mis-diagnosed. This knowledge is thought to be crucial as we know that corticosteroid treatment can show quick and dramatic response to the disease when the syndrome is early diagnosed. In this case report , a patient who is diagnosed as Hashimoto's Encephalopathy with findings of cognitive and psychotic disturbances is presented.


from Scope via xlomafota13 on Inoreader http://ift.tt/2a9lQdD
via IFTTT