Πέμπτη 16 Ιουνίου 2016

Technique: CRISP(e)R genetic mapping

Nature Reviews Genetics 17, 375 (2016). doi:10.1038/nrg.2016.68

Author: Denise Waldron

The resolution of genetic variant mapping is limited by the frequency of recombination events that occur during meiosis and disrupt linkage between adjacent markers. In a study published in Science, Sadhu et al. have circumvented this limitation in yeast by using the CRISPR–Cas



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