Extranodal Lymphoma of the Central Nervous System and Spine

Publication date: July 2016
Source:Radiologic Clinics of North America, Volume 54, Issue 4
Author(s): Kelly K. Koeller, Robert Y. Shih

Teaser

With a strong predilection for immunocompromised groups and a poorly explained increase in prevalence among those with normal immune status, lymphoma now accounts for approximately 6% of all primary brain tumors. Recent advances in multiagent chemotherapy and monoclonal antibody therapy have promoted longer-term survival, although a definitive cure remains elusive. Extranodal lymphoma of the spine is more often caused by secondary dissemination from systemic disease and less often the primary site of origin. This article reviews a broad spectrum of clinical, etiologic, and pathologic features that frequently intersect with common radiologic findings of this disease.


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