Reversed cortical over-activity during movement imagination following neurofeedback treatment for central neuropathic pain

Central neuropathic pain (CNP) is a frequent secondary consequence of spinal cord injury (SCI), affecting about 40% of patients (Siddall et al. 2003). Although CNP is caused by an injury to the somatosensory system (Haanpää et al. 2011) it can show first symptoms years after SCI. Neuroimaging studies have demonstrated changes in the resting state brain activity in the presence of CNP, which is reflected in increased thalamo-cortical coherence in the theta band (Stern et al. 2006, Sarnthein and Jeandmond 2008), as well as increased resting state EEG power and a dominant alpha frequency shift towards lower frequencies (Stern et al.

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