Nature Reviews Genetics 17, 353 (2016). doi:10.1038/nrg.2016.29
Authors: Christiaan A. de Leeuw, Benjamin M. Neale, Tom Heskes & Danielle Posthuma
The rapid increase in loci discovered in genome-wide association studies has created a need to understand the biological implications of these results. Gene-set analysis provides a means of gaining such understanding, but the statistical properties of gene-set analysis are not well understood, which compromises our
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