SEARCH FOR BIOLOGICAL ACTIVE THIAZOLIDINEDIONE: A SHORT REVIEW

2016-05-05T19-36-43Z
Source: Indo American Journal of Pharmaceutical Research
Mousumi Shyam, Biplab Debnath,* Prithesh Devbhuti.
Thiazolidinedione and its analogs are versatile substrates, which can be used for the synthesis of numerous heterocyclic compounds. Thiazolidinedione and its derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. This review covers updated information on the most active thiazolidinedione derivatives that have been reported to show considerable pharmacological actions such as antimicrobial, antiviral, anticonvulsant, anti-inflammatory and analgesic. From these results, ideas for future molecular modifications leading to compounds with greater favorable pharmacological properties may be derived. Further we can conclude that many other derivatives of thiazolidione can be synthesized which will be expected to show potent pharmacological activities.


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