Abnormal resting state brain activity in headache-free migraine patients: A magnetoencephalography study

Migraine is a common episodic neurological disorder characterized by recurrent unilateral throbbing headache and a host of complex pathophysiology including hypersensitivity to visual (photophobia), auditory (phonophobia) stimuli, nausea, emotional and motor disturbances (Headache Classification Subcommittee of the International Headache, 2004; Noseda et al., 2013; Pietrobon et al., 2013) during migraine attacks. Even in the interictal period (headache-free phase), migraine subjects also show hypersensitivity to sensory stimuli and abnormal processing of sensory information (Chen et al., 2011; Restuccia et al., 2012).

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