Πέμπτη 20 Δεκεμβρίου 2018

Mechanisms regulating zygotic genome activation

Mechanisms regulating zygotic genome activation

Mechanisms regulating zygotic genome activation, Published online: 20 December 2018; doi:10.1038/s41576-018-0087-x

The maternal-to-zygotic transition (MZT) is the process by which the transcriptionally silent embryonic genome is gradually activated. The mechanisms underlying the MZT are not fully understood, but recent work indicates that transcriptional activators have an important role.

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