NEURONOPATHY AND NEUROPATHY IN AUTOSOMAL DOMINANT SPINO-CEREBELLAR ATAXIA (SCA): A PRELIMINARY PERIPHERAL NERVE ULTRASOUND STUDY

Somatosensory or sensorimotor impairment is not uncommon in autosomal dominant spino-cerebellar ataxia (SCA) (Linnemann et al., 2015; Schöls et al., 2004), but it is unclear to what extent this is a primary peripheral nerve pathology, as typically seen in length-dependent neuropathy, or neuronopathy from neuron degeneration in dorsal root ganglia and/or anterior horn cells (van de Warrenburg et al., 2004). It is also unclear if neuropathy and neuronopathy are differently represented in the SCA subtypes.

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