Nature Reviews Genetics 18, 535 (2017). doi:10.1038/nrg.2017.46
Authors: Hervé Técher, Stéphane Koundrioukoff, Alain Nicolas & Michelle Debatisse
The interplay between replication stress and the S phase checkpoint is a key determinant of genome maintenance, and has a major impact on human diseases, notably, tumour initiation and progression. Recent studies have yielded insights into sequence-dependent and sequence-independent sources of endogenous replication stress. These
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