Κυριακή 16 Ιουλίου 2017

Dynamic chromatin technologies: from individual molecules to epigenomic regulation in cells

Nature Reviews Genetics 18, 457 (2017). doi:10.1038/nrg.2017.28

Authors: Olivier Cuvier & Beat Fierz

The establishment and maintenance of chromatin states involves multiscale dynamic processes integrating transcription factor and multiprotein effector dynamics, cycles of chemical chromatin modifications, and chromatin structural organization. Recent developments in genomic technologies are emerging that are enabling a view beyond ensemble- and time-averaged properties and



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