Κυριακή 16 Ιουλίου 2017

Disease genetics: Repeat expansion disorders — going through a phase

Nature Reviews Genetics 18, 454 (2017). doi:10.1038/nrg.2017.54

Author: Dorothy Clyde

Some common inherited diseases are caused by nucleotide repeat expansions, whereby disease occurs only when the number of repeats exceeds a critical threshold. However, the underlying molecular mechanism linking repeat number to pathology has remained elusive. A recent study provides new insight by demonstrating that



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