FORMULATION AND EVALUATION OF FAST MOUTH DISSOLVING CHEWABLE TABLET OF ALBENDAZOLE

2016-09-12T01-57-19Z
Source: Indo American Journal of Pharmaceutical Research
Dr. O. G. Bhusnure*, Shaikh Faisal Ekbal, Mane Jyoti, Sayyed Sarfaraz Ali, Hucche Bhimashankar, Surkute Ganesh.
Fast dissolving tablet format is designed to allow administration of an oral solid dose form in the absence of water or fluid intake. Such tablets readily dissolve or disintegrate in the saliva. Albendazole is anthalmentic agent which is used in disease like worms. As a vermicidal,albendazole causes degenerative alterations in the intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. It is a BCS class II drug. It exhibits poor bioavailability of about

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