Assessment of endothelial dysfunction in diabetes mellitus in Indian population by color Doppler

2016-08-26T08-01-06Z
Source: International Journal of Research in Medical Sciences
Abhilash Haridas, Payal Mukker, Sanjay Pandey, Manoj Kumar Parashar, Virender Kumar Mehta.
Background: Endothelial dysfunction is regarded as a systemic marker of cardiovascular disease. Brachial artery flow-mediated dilation (FMD) is a mode of evaluating endothelial function and for early diagnosis of atherosclerotic diseases. We studied whether there is a difference in vascular endothelial function between type 1 and 2 diabetes mellitus and normal population. Methods: We assessed %FMD of 50 patients with diabetes mellitus and 50 control populations without diabetes mellitus or other risk factors. SPSSS version 13 was used for statistical analysis. Students T test was used for comparison of means of the two groups. Results: The %FMD was significantly lower in patients with type1 and 2 diabetes mellitus compared to normal population. Conclusions: Diabetes mellitus is associated with endothelial dysfunction irrespective of Type 1 or Type 2 diabetes mellitus, as suggested by impairment in vascular reactivity to hyperemia in both. Monitoring FMD may help in assessment of progression of atherosclerosis.


from Scope via xlomafota13 on Inoreader http://ift.tt/2bDq8Ow
via IFTTT