Characteristics of local field potentials correlate with pain relief by deep brain stimulation

Neuropathic pain is one of the most debilitating diseases and it usually responds poorly to conventional pharmacological treatment (Dworkin et al., 2007; Dworkin et al., 2010; Smith, 2012). In recent years, deep brain stimulation (DBS) of the sensory thalamus, periventricular gray / periaquedauctal gray (PVAG) and anterior cingulate cortex have been used to treat neuropathic pain (Hosobuchi et al., 1973; Mazars, 1975; Bittar et al., 2005; Owen et al., 2006a, Boccard et al., 2014, Russo et al., 2015).

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