Normal pressure hydrocephalus: Increase of utricular input in responders to spinal tap test

Idiopathic normal pressure hydrocephalus (NPH) is characterized by the clinical triad of cognitive impairment, urinary incontinence and gait disturbance (Hebb et al., 2001, Relkin et al., 2005). Although this disease was first described nearly 50 years ago, (Adams et al., 1965) the pathophysiology is still under discussion. There is some evidence that increased cerebrospinal fluid (CSF) pulse pressure (Lenfeldt et al., 2004) could lead to increased liquor diapedesis in the periventricular white matter following ventricular dilatation (Kristensen et al., 1996).

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