Standardized supportive care documentation improves safety of high-dose methotrexate treatment.

Cancer shared this article with you from Inoreader Standardized supportive care documentation improves safety of high-dose methotrexate treatment. Via The Oncologist CONCLUSION: The use of standardized documentation for supportive care during HD-MTX therapy is recommended to minimize the risk of adverse events. IMPLICATIONS FOR CLINICAL PRACTICE: High-dose methotrexate (HD-MTX) is a commonly used treatment in several cancer types. Distinct supportive measures are necessary to minimize the risk of HD-MTX side effects, which can be life-threatening. Supportive care consists of certain examinations and interventions prior to starting HD-MTX and permament alkalinization of the urine, as this greatly increases the elimination of MTX and decreases the risk of kidney injury. Here we report on our findings after implementing a checklist for control of supportive care and a urine alkalinization protocol to optimize urine alkalinization. We observed a signif... View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.