Effectiveness of a Parent-led Physical Activity Intervention in Youth with Obesity

Purpose Prader-Willi Syndrome (PWS) is a complex, rare neuro-behavioral syndrome characterized by excessive fat, hypotonia, poor motor skills, and behavioral and cognitive disabilities. We tested the effectiveness of a home-based physical activity (PA) intervention led by parents in youth with obesity with and without PWS to increase moderate-to-vigorous PA (MVPA) and gross motor proficiency (MP). Methods Participants were 111 youth ages 8-16 y (45 with PWS and 66 without PWS, but categorized as obese). A parallel design was used with the control group (C) receiving the intervention after serving as control. Intervention participants (I) completed a PA curriculum four days a week for 24 weeks including warm-up exercises, strengthening exercises, and playground games two days a week and interactive console games two days a week guided by their parents. Pre-post outcomes (baseline to 24 weeks) included MVPA (7-day accelerometry) and MP including upper limb coordination, bilateral coordination, balance, running speed and agility, and muscle strength (Bruininks-Oseretsky Test of Motor Proficiency). Results The intervention led to no change in MVPA (I-group: 39.6 vs. 38.9 min/day; C-group: 40.6 vs. 38.3 min/day). The intervention led to improvements in body coordination (22.3%; p

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