Network characteristics in benign epilepsy with centro-temporal spikes patients indicating defective connectivity during spindle sleep: a partial directed coherence study of EEG signals

Benign epilepsy with centro-temporal spikes (BECTS) is the earliest recognised and most frequent form of benign focal epilepsy in childhood, accounting for 10-20% of all childhood epilepsies (Holmes, 1993). It appears in children aged 3-13 years, peaks between the ages of seven and nine years, and invariably goes into remission by the age of 14 years(Bouma et al. 1997; Callenbach et al., 2010). It may have genetic determinants with a complex inheritance pattern, but there are few genetic data available (Xiong and Zhou, 2017).

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