Ageing-related expression of Twinfilin-1 regulates cholangiocyte biological response to injury

Background and Aims: Ageing is a complex biological process that affects the functional capacity of multiple organs and is associated to the development of many diseases. Disorders affecting the biliary tree develop and progress differently according to the patient age. The aim of the study was to identify molecular pathways associated to cholangiocytes ageing and to verify their effects in the biological response to injury of biliary epithelial cells.

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